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Search Results for " xanthine oxidase-in-1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10509 Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid Xanthine Oxidase
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid ...
T0617 Nicotinamide N-oxide Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n...
TP1886L1 NoxA1ds acetate(1435893-78-9 free base) NADPH-oxidase
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col...
T78985 Xanthine oxidase-IN-11 Xanthine Oxidase
Xanthine Oxidase-IN-11, an analog of XO8, is an inhibitor of xanthine oxidase (XO) [1].
T75504 Xanthine oxidase-IN-8
Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) serves as an inhibitor of xanthine oxidase, exhibiting an inhibitory concentration (IC50) value of 29.71 μM [1].
T60626 Xanthine oxidase-IN-7
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active xanthine oxidase(XO) inhibitor (IC50 = 0.36 μM). Xanthine oxidase-IN-7 effectively reduces serum uric acid levels which has the potential in the hyperuricem...
T61092 Xanthine oxidase-IN-5
Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 μM. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic liga...
T75505 Xanthine oxidase-IN-9
Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].
T80767 Xanthine oxidase-IN-12 Xanthine Oxidase
Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally diminishing intracellular reactive oxygen species (ROS) [1].
T60632 Xanthine oxidase-IN-4
Xanthine oxidase-IN-4 (compound 19a) is an orally active and potent inhibitor of xanthine oxidase(XO) with an IC 50 of 0.039 μM that can be used in the research of hyperuricemia and gout. Xanthine oxidase-IN-4 shows hypo...
T68437 Febuxostat 67M-1
Febuxostat 67M-1 is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation.
T69281 Febuxostat 67M-4
Febuxostat 67M-4 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation.
T69282 Febuxostat 67M-2
Febuxostat 67M-2 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation.
T75949 NoxA1ds TFA
NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1), with an inhibition concentration (IC50) of 20 nM, demonstrating selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits ...
TP1886 NoxA1ds
Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Atte...
T62350 XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 is a potent inhibitor of xanthine oxidase/cyclooxygenase/lipoxygenase XO/COX/LOX. XO/COX/LOX-IN-1 can be used in the study of inflammatory, cancer and metabolic diseases.
T61060 Febuxostat sodium
Febuxostat (TEI 6720) sodium has the potential in gout and hyperuricemia research which is a potent, selective and non-purine inhibitor of xanthine oxidase (XO) with a Ki value of 0.6 nM [1] [2] [3].
T79177 URAT1&XO inhibitor 2 Xanthine Oxidase
Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for XO inhibition. It effectively impedes uric acid uptake in H...
T79175 URAT1&XO inhibitor 1 Xanthine Oxidase
URAT1&XO Inhibitor 1 (compound 29) serves as a dual inhibitor with IC50 values of approximately 10 μM for URAT1 and 1.01 μM for Xanthine Oxidase. It induces a hypouricemic effect in the potassium oxonate-induced hyperuri...
T36501 CYPMPO RR 071
CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first o...
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